| Pos | Driver | Car | No | Time | Pts |
|---|---|---|---|---|---|
| 1 | M. Bezzecchi |  Aprilia Racing | 72 | 40:50.653 | 25 |
| 2 | J. Martin | Aprilia Racing | 89 | +2.036 | 20 |
| 3 | P. Acosta |  Red Bull KTM Factory Racing | 37 | +4.497 | 16 |
| 4 | F. Di Giannantonio |  Pertamina Enduro VR46 Racing Team | 49 | +6.972 | 13 |
| 5 | M. Marquez |  Ducati Lenovo Team | 93 | +8.100 | 11 |
| 6 | E. Bastianini |  Red Bull KTM Tech3 | 23 | +8.243 | 10 |
| 7 | A. Marquez |  BK8 Gresini Racing MotoGP | 73 | +11.253 | 9 |
| 8 | R. Fernandez |  Trackhouse MotoGP Team | 25 | +13.129 | 8 |
| 9 | L. Marini |  Honda HRC Castrol | 10 | +14.471 | 7 |
| 10 | F. Bagnaia | Ducati Lenovo Team | 63 | +14.544 | 6 |
| 11 | F. Aldeguer | BK8 Gresini Racing MotoGP | 54 | +21.063 | 5 |
| 12 | B. Binder | Red Bull KTM Factory Racing | 33 | +22.062 | 4 |
| 13 | D. Moreira | Pro Honda LCR | 11 | +22.201 | 3 |
| 14 | F. Morbidelli | Pertamina Enduro VR46 Racing Team | 21 | +24.371 | 2 |
| 15 | T. Razgatlioglu |  Prima Pramac Yamaha MotoGP | 7 | +25.549 | 1 |
| 16 | J. Miller | Prima Pramac Yamaha MotoGP | 43 | +26.309 | |
| 17 | F. Quartararo |  Monster Energy Yamaha MotoGP Team | 20 | +27.136 | |
| 18 | A. Rins | Monster Energy Yamaha MotoGP Team | 42 | +38.701 | |
| J. Zarco |  Castrol Honda LCR | 5 | 18 Laps | ||
| A. Ogura | Trackhouse MotoGP Team | 79 | 15 Laps | ||
| J. Mir | Honda HRC Castrol | 36 | 5 Laps |
MotoGP - RED BULL GRAND PRIX OF THE UNITED STATES-MotoGP - Race
| POS | PILOTO | NO | TIME | PTS |
|---|---|---|---|---|
| 1 | M. BEZZECCHI Aprilia Racing | 72 | 40:50.653 | 25 |
| 2 | J. MARTIN Aprilia Racing | 89 | +2.036 | 20 |
| 3 | P. ACOSTA Red Bull KTM Factory Racing | 37 | +4.497 | 16 |
| 4 | F. GIANNANTONIO Pertamina Enduro VR46 Racing Team | 49 | +6.972 | 13 |
| 5 | M. MARQUEZ Ducati Lenovo Team | 93 | +8.100 | 11 |
| 6 | E. BASTIANINI Red Bull KTM Tech3 | 23 | +8.243 | 10 |
| 7 | A. MARQUEZ BK8 Gresini Racing MotoGP | 73 | +11.253 | 9 |
| 8 | R. FERNANDEZ Trackhouse MotoGP Team | 25 | +13.129 | 8 |
| 9 | L. MARINI Honda HRC Castrol | 10 | +14.471 | 7 |
| 10 | F. BAGNAIA Ducati Lenovo Team | 63 | +14.544 | 6 |
| 11 | F. ALDEGUER BK8 Gresini Racing MotoGP | 54 | +21.063 | 5 |
| 12 | B. BINDER Red Bull KTM Factory Racing | 33 | +22.062 | 4 |
| 13 | D. MOREIRA Pro Honda LCR | 11 | +22.201 | 3 |
| 14 | F. MORBIDELLI Pertamina Enduro VR46 Racing Team | 21 | +24.371 | 2 |
| 15 | T. RAZGATLIOGLU Prima Pramac Yamaha MotoGP | 7 | +25.549 | 1 |
| 16 | J. MILLER Prima Pramac Yamaha MotoGP | 43 | +26.309 | |
| 17 | F. QUARTARARO Monster Energy Yamaha MotoGP Team | 20 | +27.136 | |
| 18 | A. RINS Monster Energy Yamaha MotoGP Team | 42 | +38.701 | |
| - | J. ZARCO Castrol Honda LCR | 5 | 18 Laps | |
| - | A. OGURA Trackhouse MotoGP Team | 79 | 15 Laps | |
| - | J. MIR Honda HRC Castrol | 36 | 5 Laps |